molecular biologist, biochemist, researcher
Dr. Robert Melamede has a Ph.D. in Molecular Biology and Biochemistry from the City University of New York. Dr. Melamede is recognized as a leading authority on the therapeutic uses of cannabis, and has authored or co-authored dozens of papers on a wide variety of scientific subjects.
Member of several scientific boards (International Association for Cannabis as Medicine, the Scientific Advisory Board of Americans for Safe Access, Sensible Colorado, Scientific Advisor for Cannabis Therapeutics).
|2014||Cannabinoid system – physics of life and its social impact||Abstract|
This lecture will focus on how the physics, developed by Nobel laureate Ilya Prigogine, provides a basis for understanding the origins of life and evolution. We will see a unique evolutionary occurrence with the development of the vertebrate lineage. All vertebrates contain cannabinoid receptors that uniquely, homeostatically regulate all of their body systems (circulatory, digestive, immune, musculo-skeletal, nervous, reproductive, tequementary). From a holistic point of view, we will see that variations in endocannabinoid activity can have a profound effect on our social systems. In line with evolutionary history, we will see how critical it is for human survival to increase cannabinoids activity at this point in human evolution.
|2015||Life, Evolution, Endocannabinoids, and the Survival of Homo sapiens||Abstract|
Far from equilibrium thermodynamics provides a foundation for understanding life, evolution, and the unique role played by the endocannabinoid system in these processes. The metabolic underpinnings of life can be regulated by cannabinoids in order to promote health and longevity. They do so by regulating the negative effects of excess free radical production through their ability to control fat and carbohydrate metabolism. An increase in cannabinoid activity is necessary for the health modern man and human society. Marijuana has become an essential nutrient.
|2015||Evolution, Adaptability and Cannabinoids||info|
The workshop will focus on functioning and importance of cannabinoids.
|2017||The CB1 Receptor and the Evolution of Humanity, Past, Present and Future||Abstract|
In all body systems, cannabinoids, including THC, function as anti-aging compounds through their ability to inhibit the negative consequences of excess free radical production. Cannabinoids, both from the plant (phytocannabinoids) as well as those we produce (endocannabinoids) should be viewed as the “oil” of life, as an essential nutrient, as a food. They help protect us from the “friction” of life created by the free radicals that are responsible for all age-related illnesses including cancers. Keep in mind that free radicals are also necessary for life because they provide feedback control for homeostasis of all biochemistry. Free radicals are both necessary and destructive. They must be appropriately controlled for optimal survival.
THC protects differentiated cells that are, for required efficiency, largely burning free radical producing carbohydrates as fuel. THC also helps protect cells when they are overworked and producing too many free radicals by turning on safe and efficient, cellular recycling (autophagy) pathways. Autophagy occurs when cells are burning fat as their main energy source. As a consequence of cannabinoid’s ability to regulate cellular energy sources to optimize homeostasis, they have profound health benefits.
Because of their global metabolic homeostatic capacity, cannabinoids function as adaptogens. Hence, they have profound healing properties. The global cannabis awakening is driven by individuals who seethe improvement in human health that cannabis provides. All around the world, people have clearly demonstrated these benefits to themselves from direct personal experience. Cannabis benefits most of man’s illnesses becauseour endocannabinoid system is a fundamental regulator of all aspects of human existence. The use of genetic engineering, to eliminate the CB1 receptor in a strain of mice,thereby creating a knockout mouse, has demonstrated the essential nature of CB1 activity. These mice die very prematurely, and are too afraid to move around the cage because they're so stressed without any CB1 simulation.
Today, the greatest global harm to humanity
results from illnesses that characteristically produce excess free radicals.
HIV, for example, has evolved in the highly differentiated immunological cells
of primates and man. It requires the carbohydrate-based metabolic machinery
that supported its evolution. When electron transport carbohydratecatabolism is
reduced sufficiently, and replaced by safer fat burning, the viral infective
process does not have the energy and resource support required for a successful
The cannabis awakening is spreading around the world because of the beneficial experiences that people everywhere are having. People are demanding change. As governments protect the special interests that have helped support them, many people are choosing safer, cheaper more efficacious cannabis-based medicines and nutritional support. High THC, whole plant cannabis oil extracts can efficiently and effectively control both HIV and Kaposi sarcoma.
HIV is the leading cause of death on the
African continent. Most people infected with the virus go untreated. HIV can
inexpensively and successfully be controlled with cannabis extracts in the
absence of antiretroviral drugs. HIV-associated Kaposi's sarcoma is the number
one cancer in Africa. There is no effective treatment for people suffering from
Kaposi. They die painful horrible deaths. Cannabis extracts completely
control this deadly virus-induced cancer.
The scientific perspective presented can be extended to metabolic syndrome and it's associated consequences, heart disease and diabetes. Additionally, The matrilineal inheritance of mitochondria is readily explainable.
The medicinal, nutritional and industrial
benefits documented herein only scratch the surface of the benefits that this
plant can provide humanity now that the true value of the cannabis plant is
becoming common knowledge. People resist change, but most will embrace it when
it cures cancer and relieves pain and suffering. The synergy between the
people's observations and modern science makes the continued expansion of
cannabis use inevitable, unstoppable and irreversible.
Cannabinoids fine-tune a cell's energy production in order to protect it from excess free radical production. Consequently, cannabinoids have allowed for the evolution of the vertebrate brain, reaching its high point with humans. Evolution is the direct manifestation of the universal creative force. It selects for adaptability. The entire biosphere is one large unfolding chemical reaction. All life forms are simply quantized probes for adaptability. There is a constant back-and-forth between an organism adapting to his changing environment and changing its environment by doing so.
Today the planet is undergoing a far from equilibrium phase change. The fluctuations of all the variables representing man’s interface with nature, and of nature itself, have become extreme. The decline of species, the variability of nature's chemicals interactions altered by man-made pollutants, the fluctuations of our financial establishments, of human migration, and of human behavior in general, are indicators of the gross rearrangement that has begun. It will result in either the collapse of societies or their rearrangement into a more cooperative, peaceful, and healthy world as cannabinoid content of human biochemistry globally increases as it always has.
|2017||The CB1 Receptor and the Evolution of Humanity, Past, Present and Future||Workshop|